I for one have always been opposed to marketing ED's with alcohol. Mixing a stimulant with a depressant creates chaos for the central nervous system.
With that being said, The big guys shy away from the marketing because of a percieved "social responsibilty" that goes along with being industry leaders, nevermind that one of the big guys got there by the very same marketing that they now disavow.(by a strong court recommendation nonetheless).
Large ED companies do have a responsibilty to advertise their product responsibly to the demographics due to the liability they hold. A company worth $300 mm is more apt to get sued over a "situation" or "incident" than a smaller company with no market capitalization. Therefore, the smaller company, being naive, and having less "exposure" is more willing to take the risk.
As far as your statement "Do the big companies really think their denial is going to protect them " I give you this. What are they denying? Are they denying that customers or bars use their product in a way that it is not intended? The majors can not babysit their consumers, there must be some consumer culpability here. If the majors shy away form direct or indirect marketing of ED's mixing with alcohol I do not think they are on the hook......However, in the ever increasing "nanny state" we are heading down it seems that the manufacturers must warn consumers from themselves and if they don't then it is the manufacturers fault.
Whether you think can or think you can\'t, you\'re probably right!