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brief aspartame review: formaldehyde toxicity: Murray 9.4.3 rmforall

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  • brief aspartame review: formaldehyde toxicity: Murray 9.4.3 rmforall
    brief aspartame review: formaldehyde toxicity: Murray 9.4.3 rmforall

    Rich Murray, MA Room For All
    1943 Otowi Road, Santa Fe, New Mexico 87505 USA 505-986-9103

    [NutraSweet, Equal, Canderel, Benevia, E951]
    aspartame review: methanol, formaldehyde, formic acid toxicity:
    Murray 9.4.3 rmforall
    formaldehyde from methanol in aspartame: Murray: 12.9.2 rmforall
    aspartame & formaldehyde toxicity: Murray 9.4.3 rmforall
    EU votes 440 to 20 to approve sucralose, limit cyclamates & reevaluate
    aspartame & stevia: Murray 4.12.3 rmforall
    Mark Gold exhaustively critiques European Commission Scientific
    Committee on Food re aspartame (12.4.2): 59 pages, 230 references
    aspartame toxicity coverup increases danger of corporate meltdown:
    Michael C. Carakostas of Coca-Cola: Murray 8.11.3 rmforall
    The International Society of Regulatory Toxicology and Pharmacology
    Carakostas, Michael C., DVM, PhD
    Director/Scientific & Regulatory Affairs
    The Coca-Cola Company PO Drawer 1734 Atlanta, GA 30301
    T. 404/676-4234 F. 404/676-7166 E-mail: [photo]
    Aspartame: The world agrees it's safe By Michael Carakostas, DVM, PhD
    Director, Scientific and Regulatory Affairs, Coca-Cola

    It is commendable that Carakostas mentions the core problem, albeit
    disparagingly: "During digestion, aspartame yields a very small amount
    of methanol-- as do many other food substances. The body converts this
    methanol to formaldehyde, which is instantly converted to formate.
    Formate is quickly eliminated as carbon dioxide and water."

    Plenty of evidence in the mainstream scientific literature since 1973
    shows that as much as 30% of the formaldehyde is retained in the body as
    toxic, cumulative adducts to the DNA, RNA, and proteins in all cells and
    tissues, leading to pointed reports by informed doctors and experts.
    Clearly, there are no safe levels for chronic, low-level formaldehyde
    exposure. If just 10% of the methanol from six cans of diet soda is
    retained in the body as toxic products of formaldehyde and formic acid,
    that is sixty times the EPA limit for allowable formaldehyde from daily
    drinking water.
    President Bush & formaldehyde (aspartame) toxicity: Ramazzini Foundation
    carcinogenicity results Dec 2002: Soffritti: Murray 8.3.3 rmforall

    p. 88 "The sweetening agent aspartame hydrolyzes in the gastrointestinal
    tract to become free methyl alcohol, which is metabolized in the liver
    to formaldehyde, formic acid, and CO2. (11)" Medinsky MA & Dorman DC.
    1994; Assessing risks of low-level methanol exposure. CIIT Act. 14: 1-7.

    Ann N Y Acad Sci. 2002 Dec; 982: 87-105.
    Results of long-term experimental studies on the carcinogenicity of
    formaldehyde and acetaldehyde in rats.
    Soffritti M, Belpoggi F, Lambertin L, Lauriola M, Padovani M, Maltoni C.
    Cancer Research Center, European Ramazzini Foundation for Oncology
    and Environmental Sciences, Bologna, Italy.

    "Formaldehyde and acetaldehyde were found to produce an increase in
    total malignant tumors in the treated groups and showed specific
    carcinogenic effects on various organs and tissues. PMID: 12562630"

    It is certain that high levels of aspartame use, above 2 liters daily
    for months and years, must lead to chronic formaldehyde-formic acid
    toxicity, since 11% of aspartame (1,120 mg in 2L diet soda, 5.6 12-oz
    cans) is 123 mg methanol (wood alcohol), immediately released into the
    body after drinking (unlike the large levels of methanol locked up in
    molecules inside many fruits), then quickly transformed into
    formaldehyde, which in turn becomes formic acid, both of which in
    time are partially eliminated as carbon dioxide and water.

    However, about 30% of the methanol remains in the body as cumulative
    durable toxic metabolites of formaldehyde and formic acid-- 37 mg daily,
    a gram every month. [J. Nutrition 1973 Oct; 103(10): 1454-1459.
    Metabolism of aspartame in monkeys. Oppermann JA, Muldoon E,
    Ranney RE.] If 10% of the methanol is retained as formaldehyde,
    that would give 12 mg daily formaldehyde accumulation, about 60 times
    more than the 0.2 mg from 10% retention of the 2 mg EPA daily limit
    for formaldehyde in water.

    Many scientific studies and case histories report: * headaches
    * many body and joint pains (or burning, tingling, tremors, twitching,
    spasms, cramps, or numbness) * fever, fatigue
    * "mind fog", "feel unreal", poor memory, confusion, anxiety,
    irritability, depression, mania, insomnia, dizziness, slurred speech,
    ringing in ears, sexual problems, poor vision, hearing, or taste
    * red face, itching, rashes, hair loss, burning eyes or throat,
    dry mouth or eyes, mouth sores * obesity, bloating, edema, anorexia,
    poor or excessive hunger or thirst * breathing problems
    * nausea, diarrhea or constipation * coldness * sweating
    * racing heart, high blood pressure, erratic blood sugar levels
    * seizures * birth defects * brain cancers * addiction
    * aggrivates diabetes, autism, allergies, ADHD, fibromyalgia,
    chronic fatigue syndrome, multiple chemical sensitivity, multiple
    sclerosis, and interstitial cystitis (bladder pain).
    RTM: Smith, Terpening, Schmidt, Gums:
    full text: aspartame, MSG, fibromyalgia 1.17.2 rmforall
    Jerry D Smith, Chris M Terpening, Siegfried OF Schmidt, and John G Gums
    Siegfried O. Schmidt, MD Asst. Clinical Prof.
    Relief of Fibromyalgia Symptoms Following Discontinuation of Dietary
    Excitotoxins. The Annals of Pharmacotherapy 2001; 35(6): 702-706.
    Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL, USA.
    CASE SUMMARY: Four patients diagnosed with fibromyalgia syndrome
    for two to 17 years are described. All had undergone multiple treatment
    modalities with limited success. All had complete, or nearly complete,
    resolution of their symptoms within months after eliminating monosodium
    glutamate (MSG) or MSG plus aspartame from their diet. All patients
    were women with multiple comorbidities prior to elimination of MSG.
    All have had recurrence of symptoms whenever MSG is ingested.
    aspartame in Merck Maxalt-MLT worsens migraine: Murray 7.16.2 rmforall
    Migraine MLT-Down: an unusual presentation of migraine
    in patients with aspartame-triggered headaches.
    Newman LC, Lipton RB Headache 2001 Oct; 41(9): 899-901.
    [Merck 10-mg Maxalt-MLT, for migraine, has 3.75 mg aspartame,
    while 12 oz diet soda has 200 mg.]
    Headache Institute, St. Lukes-Roosevelt Hospital Center, New York, NY
    Department of Neurology
    Albert Einstein College of Medicine, Bronx, NY
    Innovative Medical Research
    aspartame puts formaldehyde adducts into tissues, Part 1/2
    full text, Trocho & Alemany 6.26.98: Murray 12.22.2 rmforall
    Formaldehyde derived from dietary aspartame binds to tissue
    components in vivo. Life Sci 1998 Jun 26; 63(5): 337-49.
    Maria Alemany, PhD (male)

    Confirming evidence and a general theory are given by Pall (2002):
    testable theory of MCS type diseases, vicious cycle of nitric oxide &
    peroxynitrite: MSG: formaldehyde-methanol-aspartame:
    Martin L. Pall: Murray: 12.9.2 rmforall
    Functional Therapeutics in Neurodegenerative Disease Part 1/2:
    Perlmutter 7.15.99: Murray 1.10.3 rmforall
    formaldehyde toxicity: Thrasher & Kilburn: Shaham: EPA: Gold: Murray:
    Wilson: CIIN: 12.12.2 rmforall
    24 recent formaldehyde toxicity [Comet assay] reports:
    Murray 12.31.2 rmforall
    genotoxins, Comet assay in mice: Ace-K, stevia fine; aspartame poor;
    sucralose, cyclamate, saccharin bad: Y.F. Sasaki Aug 2002:
    Murray 1.27.3 rmforall [A detailed look at the data] 5-page review
    Roberts HJ Aspartame (NutraSweet) addiction.
    Townsend Letter 2000 Jan;
    Sunshine Sentinel Press P.O.Box 17799 West Palm Beach, FL 33416
    800-814-9800 561-588-7628 561-547-8008 fax 603-225-2100
    Aspartame Toxicity Information Center Mark D. Gold 12 East Side Drive #2-18 Concord, NH 03301
    "Scientific Abuse in Aspartame Research" 1023 articles 15771 posts 715 members
    ************************************************** ************************************************
    Send blank post to: <br /> to join<br />free,open, list with searchable archives for toxicity issues.<br />Richard \"Rich\" T. Murray Room For All 1943 Otowi Road Santa Fe, NM 87505<br /> 505-501-2298