Senomyx announces receipt of milestone payment from the Coca-Cola Company

SAN DIEGO, CA – October 28, 2008 /PRNewswire-FirstCall/ — Senomyx, Inc.(NASDAQ:SNMX), a leading company focused on using proprietary technologies to discover and develop novel flavor ingredients for the food, beverage and ingredient supply industries, announced today that it has received a payment from The Coca-Cola Company(NYSE:KO)related to a milestone achieved by Senomyx under the companies’ collaborative research, development, commercialization and license agreement. The milestone was associated with Senomyx’s discovery of a promising new flavor ingredient.

“Senomyx has accomplished an important milestone under our collaboration with The Coca-Cola Company, the world’s largest beverage company,” noted Kent Snyder, President and Chief Executive Officer of the Company. “This is an exciting time for Senomyx as we continue development activities with a new flavor ingredient that can be used to reduce the amount of sugar in beverages and foods while retaining the desired taste.”

About Senomyx, Inc. ( )

Senomyx is a leading company using proprietary taste receptor technologies to discover and develop novel flavor ingredients in the savory, sweet, salt, bitter, and cooling areas. Senomyx has entered into product discovery and development collaborations with seven of the world’s leading food, beverage, and ingredient supply companies: Ajinomoto Co., Inc., Cadbury plc, Campbell Soup Company, The Coca-Cola Company, Firmenich SA, Nestle SA, and Solae. Nestle is currently marketing products that contain one of Senomyx’s flavor ingredients. For more information, please visit .